General Notes
This product (Catalog No. DPABH-17626) is a rabbit-derived polyclonal antibody raised against human DNALI1, targeting the amino acid region 60–143 of the protein. It has been affinity purified by Protein A. DNALI1 (dynein axonemal light intermediate chain 1) encodes a component of the axonemal dynein motor complex that is essential for ciliary and flagellar motility. DNALI1 is expressed in tissues containing motile cilia, such as the respiratory tract and reproductive system, where it contributes to microtubule-based sliding required for coordinated ciliary beating. As part of the dynein complex, DNALI1 helps regulate ATP-dependent mechanical force generation and intracellular transport along microtubules. Defects or altered expression of DNALI1 may be associated with impaired ciliary function and have been implicated in ciliopathy-related disorders. Overall, DNALI1 plays an important role in maintaining normal mucociliary clearance and cellular motility processes.
DPABH-17626 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-17626 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.