Rabbit Anti-Human DNALI1 (a.a. 1-258) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human DNALI1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-258 aa of BC046117

Conjugate

Application Notes

WB: 1:2000-1:10000
IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate

General Notes

This product (Catalog No. DPABH-05156) is a rabbit-derived polyclonal antibody raised against human DNALI1, targeting the amino acid region 1–258 of the protein. This antibody exhibits cross-reactivity with Human DNALI1 from mouse and rat. It has been affinity purified by Protein A. DNALI1 belongs to the inner dynein arm light chain family and encodes a subunit of the light intermediate chain of inner dynein arms of the axoneme of sperm flagella (PMID: 36792588). DNALI1 promotes neurodegeneration after traumatic brain injury via inhibition of autophagosome-lysosome fusion (PMID: 38348540). Mutation in DNALI1 Causes Male Infertility with Severe Oligoasthenoteratozoospermia in Humans (PMID: 38212584).
DPABH-05156 is suitable for use in Western blot (WB) (1:2,000–1:10,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate) applications.
DPABH-05156 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

hp28; P28

Entrez Gene ID

UniProt ID