DKK1 (NP_036374, 81 a.a. ~ 180 a.a) partial recombinant protein with GST tag. The sequence is QPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVS SDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYH
Conjugate
Unconjugated
Target
Alternative Names
DKK1; dickkopf WNT signaling pathway inhibitor 1; SK; DKK-1; dickkopf-related protein 1; hDkk-1; dickkopf-1 like; dickkopf 1 homolog; dickkopf-like protein 1; dickkopf related protein-1;
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Pathway
Cardiac Progenitor Differentiation; Presenilin action in Notch and Wnt signaling; Signal Transduction; TCF dependent signaling in response to WNT
Citations
Publication ()
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