General Notes
This product (Catalog No. DPABH-11805) is a rabbit-derived polyclonal antibody raised against human DIO1, targeting the amino acid region 89–254 of the protein. This antibody exhibits cross-reactivity with Human DIO1 from mouse and rat. It has been affinity purified by Protein A. DIO1 (Type I iodothyronine deiodinase) is a selenium-dependent enzyme, encoded by the DIO1 gene, that acts as a key regulator of thyroid hormone activation, primarily converting inactive T4 to active T3 in peripheral tissues like the liver and kidneys. It also contributes to T3 pool, aids in iodine recycling, and is regulated by thyroid status, selenium levels, and specific genetic variants (e.g., SNP rs2235544).
DPABH-11805 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:500–1:4,000) applications.
DPABH-11805 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
Publication 
Loading ......
