Anti-DGCR2 (aa 251-300) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide: WHAESCYEKS SFLCKRSQTC VDIKDNVVDE GFYFTPKGDD PCLSCTCHGG , corresponding to internal sequence amino acids 251-300 of Human DGCR2 (accession number: NP_005128)

Conjugate

Application Notes

WB: 1 μg/ml;

Alternative Names

DGCR2; DiGeorge syndrome critical region gene 2; IDD; LAN; DGS-C; SEZ-12; integral membrane protein DGCR2/IDD; DiGeorge syndrome critical region protein 2; integral membrane protein deleted in DiGeorge syndrome;

Entrez Gene ID

UniProt ID

Antigen Description

The DGCR2 gene encodes a novel putative adhesion receptor protein, which may play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22.