A synthetic peptide of human DGCR2 is used for rabbit immunization.
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Unconjugated
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Alternative Names
DGCR2; DiGeorge syndrome critical region gene 2; IDD; LAN; DGS-C; SEZ-12; integral membrane protein DGCR2/IDD; DiGeorge syndrome critical region protein 2; integral membrane protein deleted in DiGeorge syndrome;
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.
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