General Notes
This product (Catalog No. DPABH-05810) is a rabbit-derived polyclonal antibody raised against human DEDD, targeting the amino acid region 191–318 of the protein. It has been affinity purified by Protein A. DEDD, or death effector domain containing protein, is a 37 kDa multifunctional protein encoded by the human DEDD gene located on chromosome 1q23.3, featuring an N-terminal death effector domain (DED) that facilitates protein-protein interactions in apoptotic signaling pathways, along with a C-terminal region homologous to histones and nuclear localization signals that enable its translocation from the cytoplasm to the nucleus and nucleolus. The protein is highly conserved across species, sharing 98.7% identity between human and mouse orthologs, and is ubiquitously expressed in human tissues.
DPABH-05810 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-05810 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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