DEDD (NP_127491, 91 a.a. ~ 190 a.a) partial recombinant protein with GST tag. The sequence is IITRHDLLPYVTLKRRRAVCPDLVDKYLEETSIRYVTPRALSDPEPRPPQPSKTVPPHYP VVCCPTSGPQMCSKRPARGRATLGSQRKRRKSVTPDPKEK
Conjugate
Unconjugated
Target
Alternative Names
DEDD; death effector domain containing; DEFT; KE05; DEDD1; FLDED1; CASP8IP1; death effector domain-containing protein; DEDPro1; FLDED-1; death effector domain-containing testicular molecule;
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
Citations
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A: DPAB-DC3751 antibody store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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