Specifications
Immunogen
Recombinant full length protein corresponding to Human DCK (NP_000779) produced in HEK293T cells.
Applications
Application Notes
WB: 1/2000; Flow Cyt: 1/100;
Target
Alternative Names
DCK; deoxycytidine kinase; deoxynucleoside kinase; MGC117410; MGC138632;
Product Background
Antigen Description
Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
Pathway
Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Purine salvage, organism-specific biosystem;
Citations
Publication ()
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COA
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