Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.
Pathway
BMP receptor signaling; Developmental Biology; Regulation of Signaling by NODAL; Signal Transduction; Signaling by BMP; Signaling by NODAL; Wnt signaling pathway
Citations
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