Specifications
Immunogen
Recombinant protein corresponding to human CER1.
Applications
Application Notes
WB (1:500-1:2000); Immunohistochemistry (1:200-1:1000); ELISA (1:10000) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
CER1; cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis); cerberus 1 (Xenopus laevis) homolog (cysteine knot superfamily); cerberus; DAND4; cerberus-related 1; cerberus-related protein; DAN domain family member 4; MGC96951; MGC119894; MGC1198
Product Background
Antigen Description
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity.
Pathway
BMP receptor signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem;
Citations
Publication ()
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COA
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