Specifications
Species Reactivity
Mouse; Rat; Human; Rhesus monkey
Immunogen
N-terminal peptide (aa. 2-38) of mouse CCR6 fused with GST
Conjugate
Alexa Fluor 647
Applications
Application Notes
For immunofluorescent staining, the suggested use of this reagent is ≤0.25 μg per million cells in 100 μl volume.
Target
Alternative Names
CCR6; chemokine (C-C motif) receptor 6; C-C chemokine receptor type 6; CCR-6; KY411; Cmkbr6; CC-CKR-6;
Product Background
Antigen Description
CCR6 is a G-protein linked chemokine receptor which binds the chemokine CCL20/MIP-3a. It is expressed on B lymphocytes and certain subsets of dendritic cells and T cells. CCR6 in reported to be involved in mucosal immune response and lymphocyte migration
Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem;
Citations
Publication ()
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COA
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