Synthetic peptide corresponding to residues near the N terminal of human chemokine (C-C motif) receptor 6
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:1000-1:5000 IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-00390) is a rabbit-derived IgG polyclonal antibody raised against human CCR6. It has been affinity purified by protein A. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. DPABH-00390 is suitable for use in Western blot (WB) (1:1,000–1:5,000), IHC (1:50–1:200) applications. DPABH-00390 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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