Anti-CCL3 polyclonal antibody [Biotin] (DPABY-384)

Goat Anti-Human CCL3 polyclonal antibody for WB, ICC, ELISA(Det)

Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
E. coli-derived recombinant human CCL3/MIP-1 alpha . Ala27-Ala92 Accession Number P10147
Conjugate
Biotin

Applications


Application Notes
Western Blot 0.1 μg/mL; Immunocytochemistry 5-15 μg/mL; ELISA Capture 0.2-0.8 μg/mL; ELISA Detection 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DPABY-272 - DPABY-384
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CCL3; chemokine (C-C motif) ligand 3; MIP1A; SCYA3; G0S19-1; LD78ALPHA
Entrez Gene ID
UniProt ID

Product Background


Pathway
Chagas disease (American trypanosomiasis); Chemokine receptors bind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokine-cytokine receptor interaction; GPCR ligand binding; IL12-mediated signaling events; Peptide ligand-

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References


Huang, G; Mo, XX; et al. Autoantibodies to CCL3 are of low sensitivity and specificity for the diagnosis of type 1 diabetes. ACTA DIABETOLOGICA 49:395-399(2012).
Kasama, T; Isojima, S; et al. Serum macrophage migration inhibitory factor levels are correlated with response to tocilizumab therapy in patients with rheumatoid arthritis. RHEUMATOLOGY INTERNATIONAL 34:429-433(2014).

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