Anti-CYSLTR2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human CYSLTR2 is used for rabbit immunization.

Conjugate

Alternative Names

CYSLTR2; cysteinyl leukotriene receptor 2; HG57; CYSLT2; HPN321; CYSLT2R; KPG_011; hGPCR21; PSEC0146; G protein-coupled receptor; G-protein coupled receptor HG57; G-protein coupled receptor GPCR21; cysteinyl leukotriene CysLT2 receptor;

Entrez Gene ID

UniProt ID

Antigen Description

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems.

Pathway

Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); Eicosanoid ligand-binding receptors; Endothelins; G alpha (q) signalling events; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like; Gastrin-CREB signalling pathway via PKC and MAPK; Leukotriene receptors; Neuroactive ligand-receptor interaction;