Anti-CYP4X1 monoclonal antibody (DCABH-11205) Made to order

Rabbit anti-Human CYP4X1 monoclonal antibody for WB, ELISA

View other CYP4X1 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human CYP4X1 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
CYP4X1; cytochrome P450, family 4, subfamily X, polypeptide 1; cytochrome P450 4X1; MGC40051; CYPIVX1
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CYP4X1 (Cytochrome P450 Family 4 Subfamily X Member 1) is a Protein Coding gene. Among its related pathways are Tryptophan metabolism and Circadian entrainment. GO annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP4F8. This gene encodes a member of the cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants.
Antigen Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Protein Symbol:Q8N118-CP4X1_HUMANRecommended name:Cytochrome P450 4X1Protein Accession:Q8N118Secondary Accessions:G3V1U1Q5VVE5Q6ZN67Q8NAZ3CYP4X1 (cytochrome P450, family 4, subfamily X, polypeptide 1) is a protein which in humans is encoded by the CYP4X1 gene. 0The function about CYP4X1 antigen include aromatase activity; electron carrier activity; heme binding; metal ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen.
Pathway
Serotonergic synapse, organism-specific biosystem; acetone degradation I (to methylglyoxal), organism-specific biosystem; bupropion degradation, organism-specific biosystem; melatonin degradation I, organism-specific biosystem; nicotine degradation II, organism-specific biosystem; nicotine degradation III, organism-specific biosystem; superpathway of melatonin degradation, organism-specific biosystem.

Citations


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References


Al-Anizy, M; Horley, NJ; et al. Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain. FEBS JOURNAL 273:936-947(2006).
Al-Anizy, M; Bell, DR; et al. Characterisation of CYP4X1, a novel cytochrome P450. TOXICOLOGY 202:100-100(2004).

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