Specifications
Immunogen
Synthetic peptide conjugated to KLH, corresponding to a sequence within C terminal amino acids 454-484 of Human CYP2A13.
Applications
Application Notes
WB: 1/50 - 1/100; IHC-P: 1/50 - 1/100; Flow Cyt: 1/10 - 1/50.
Target
Alternative Names
CYP2A13; cytochrome P450, family 2, subfamily A, polypeptide 13; cytochrome P450, subfamily IIA (phenobarbital inducible), polypeptide 13; cytochrome P450 2A13; CPAD; CYP2A; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13; CYPIIA1
Product Background
Antigen Description
Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity.
Pathway
Biological oxidations; Caffeine metabolism; Cytochrome P450 - arranged by substrate type; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes;
Citations
Publication ()
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COA
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