Anti-CXCL6 polyclonal antibody [Biotin]

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

E. coli-derived recombinant human CXCL6/GCP-2 . Val40-Asn114 Accession Number P80162

Conjugate

Application Notes

Western Blot: 0.1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4121 - DPABY-522

Alternative Names

CXCL6; chemokine (C-X-C motif) ligand 6; GCP2; CKA-3; GCP-2; SCYB6; C-X-C motif chemokine 6; chemokine alpha 3; small-inducible cytokine B6; granulocyte chemotactic protein 2; Small inducible cytokine subfamily B (Cys-X-Cys), member b; chemokine (C-X-C mo

Entrez Gene ID

UniProt ID

Antigen Description

GCP-2 (granulocyte chemotactic protein-2) is a CXC chemokine. Among human CXC chemokines, GCP-2 is most closely related to ENA-78. The structure and sequence of the genes for human GCP-2 and ENA-78 also exhibit close similarity, suggesting the two genes may have originated from a recent gene duplication. LIX (LPS-induced CXC chemokine) was initially cloned as a gene induced by LPS in mouse fibroblasts. The mouse protein designated GCP-2, because of its amino acid sequence similarity (60%) to human GCP-2, is identical to the LIX protein sequence.

Pathway

Chemokine receptors bind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokine-cytokine receptor interaction; G alpha (i) signalling events; GPCR downstream signaling; GPCR ligand binding; Peptide ligand-binding receptors