Anti-CXCL6 polyclonal antibody [Biotin]

Antibody Isotype

IgG

Species Reactivity

Rat

Immunogen

E. coli-derived recombinant rat LIX. Ala38-Arg125 Accession Number P97885

Conjugate

Application Notes

Western Blot: 0.1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4149 - DPABY-414

Alternative Names

CXCL6; chemokine (C-X-C motif) ligand 6; Cxcl5; C-X-C motif chemokine 5; cytokine LIX; CXC chemokine LIX; small-inducible cytokine B5; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2);

Entrez Gene ID

UniProt ID

Antigen Description

LPS-induced CXC chemokine (LIX) is a member of the murine chemokine family. It is 132 amino acids (aa) in length with a predicted molecular weight of 14 kDa prior to cleavage of the N-terminal signal peptide (aa 1–40). LIX has no true human ortholog but is closely related to human CXCL5/ENA-78 and CXCL6/GCP-2. It is widely expressed, and is secreted by multiple cell types including fibroblasts, thymic epithelium, platelets, vascular endothelium, and hepatocytes. LIX acts as a proinflammatory chemokine and is chemotactic for neutrophils.

Pathway

Chemokine signaling pathway; Pertussis; Rheumatoid arthritis;