Specifications
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human CXCL13. The sequence is KNKSIVCVDPQAE
Applications
Application Notes
ELISA: 1:32000. & The optimal working dilution should be determined by the end user.
Target
Alternative Names
CXCL13; chemokine (C-X-C motif) ligand 13; BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13; C-X-C motif chemokine 13; CXC chemokine BLC; B-cell chemoattractant; B-lymphocyte chemoattractant; b lymphocyte chemoattractant; small-inducible cytokine B13; B-cel
Product Background
Antigen Description
B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyers patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitts lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.
Pathway
CXCR3-mediated signaling events; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokine-cytokine receptor interaction
Citations
Publication ()
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COA
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