Specifications
Species Reactivity
Mouse; Human
Immunogen
A synthetic peptide corresponding to residues on the C terminus of human Cathepsin D.
Applications
Application Notes
WB: 1/2000 - 1/10000; IP: 1/10; IHC-P: 1/500 - 1/1000; ICC: 1/250 - 1/1000; Flow Cyt: 1/20 - 1/100;
Target
Alternative Names
CTSD; cathepsin D; cathepsin D (lysosomal aspartyl protease) , CPSD; ceroid lipofuscinosis; neuronal 10; CLN10; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; CPSD; MGC2311;
Product Background
Antigen Description
Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Pathway
Ceramide signaling pathway, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; LKB1 signaling events, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem;
Citations
Publication ()
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COA
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