Processively dephosphorylates Ser-2 and Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II.
Pathway
Abortive elongation of HIV-1 transcript in the absence of Tat; Formation of HIV elongation complex in the absence of HIV Tat; Formation of RNA Pol II elongation complex; Formation of the HIV-1 Early Elongation Complex
Citations
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