CSTF3 (cleavage stimulation factor subunit 3) is required for polyadenylation and 3-end cleavage of mammalian pre-mRNAs and is part of the CSTF complex. The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). CSTF3 functions as a homodimer and interacts directly with CSTF1 and CSTF2.
Pathway
Cleavage of Growing Transcript in the Termination Region; Gene Expression; Processing of Capped Intron-Containing Pre-mRNA; Processing of Capped Intronless Pre-mRNA; Processing of Intronless Pre-mRNAs; RNA Polymerase II Transcription; RNA Polymerase II Tr
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