Anti-CSF3R (aa 25-134) polyclonal antibody

Species Reactivity

Human

Immunogen

CSF3R (AAH53585, 25 a.a. ~ 134 a.a) partial recombinant protein with GST tag. The sequence is ECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLGAELQPGGRQQRLSDGTQE SIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLMN

Conjugate

Alternative Names

CSF3R; colony stimulating factor 3 receptor (granulocyte); CD114; GCSFR; granulocyte colony-stimulating factor receptor; G-CSF-R; CD114 antigen; G-CSF receptor;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Pathway

Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Pathways in cancer;