Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) to residues in the intracellular domain of Human GCSF Receptor. (Q99062).
Applications
Application Notes
WB: 1/1000 - 1/10000; Flow Cyt: 1/500 - 1/1000.
Target
Alternative Names
CSF3R; colony stimulating factor 3 receptor (granulocyte); CD114; granulocyte colony-stimulating factor receptor; GCSFR; G-CSF-R; CD114 antigen; G-CSF receptor;
Product Background
Antigen Description
Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
Pathway
Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; Pathways in cancer, organism-specific biosystem;
Citations
Publication ()
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COA
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