Specifications
Species Reactivity
Mouse; Human; Zebrafish
Immunogen
Recombinant fragment within Human Citrate synthetase aa 44-346. The exact sequence is proprietary.Database link: O75390
Applications
Application Notes
WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/1000;
Target
Alternative Names
CS; citrate synthase; citrate synthase, mitochondrial;
Product Background
Antigen Description
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found.
Pathway
Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, organism-specific biosystem; Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, conserved biosystem; Citric acid cycle (TCA cycle), organism-specific biosystem;
Citations
Publication ()
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COA
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