RAIDD antibody was raised against a peptide corresponding to amino acids 99 to 117 of human RAIDD .
Conjugate
Unconjugated
Target
Alternative Names
CRADD; CASP2 and RIPK1 domain containing adaptor with death domain; MRT34; RAIDD; death domain-containing protein CRADD; death adaptor molecule RAIDD; caspase and RIP adaptor with death domain; RIP-associated protein with a death domain; RIP-associated IC
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008]
Pathway
Apoptosis; Apoptosis Modulation and Signaling; Caspase cascade in apoptosis; Ceramide signaling pathway; HIV-1 Nef: Negative effector of Fas and TNF-alpha; TNF-alpha/NF-kB Signaling Pathway
Citations
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COA
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