Tag/Conjugate
Unconjugated
SequenceSimilarities
19 amino acids near the center of human RAIDD.
Purity
> 95 % by SDS-PAGE.
Preservative
0.02% Sodium Azide
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. PBS with 0.1% BSA 0.02% sodium azide pH7.2
Reconstitution
CRADD peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.
Introduction
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008]
Synonyms
CRADD; CASP2 and RIPK1 domain containing adaptor with death domain; MRT34; RAIDD; death domain-containing protein CRADD; death adaptor molecule RAIDD; caspase and RIP adaptor with death domain; RIP-associated protein with a death domain; RIP-associated ICH1/CED3-homologous protein with death domain;
Citations
Publication ()
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COA
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