Recombinant human CORO1C protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-306 aa of BC002342
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:3000 IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate IHC: 1:100-1:500 IF/ICC: 1:200-1:800
General Notes
This product (Catalog No. DPABH-01493) is a rabbit-derived polyclonal antibody raised against human CORO1C, targeting the amino acid region 1–306 of the protein. This antibody exhibits cross-reactivity with Human CORO1C from mouse and rat. It has been affinity purified by Protein A. CORO1C also known as HCRNN4, belongs to the WD repeat coronin family. CORO1C contains 5 N-terminal trp-asp (WD) repeats and a C-terminal coiled-coil motif. It was reported to regulate actin-dependent processes by assembling F-actin. CORO1C promoted the invasion of breast cancer and glioma cells by specifically promoting the formation of invadopodia(PMID: 30974047). DPABH-01493 is suitable for use in Western blot (WB) (1:500–1:3,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:100–1:500), IF/ICC (1:200–1:800) applications. DPABH-01493 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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