Mouse anti-Human COPS3 polyclonal antibody

Species Reactivity

Human

Immunogen

COPS3 (NP_003644, 324 a.a. ~ 422 a.a) partial recombinant protein with GST tag. The sequence is SRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKC IELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSY

Conjugate

Alternative Names

COPS3; COP9 signalosome subunit 3; CSN3; SGN3; COP9 signalosome complex subunit 3; signalosome subunit 3; COP9 complex subunit 3; JAB1-containing signalosome subunit 3; COP9 constitutive photomorphogenic homolog subunit 3;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene.

Pathway

TNF-alpha/NF-kB Signaling Pathway;