The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Inoue, K; Mineharu, Y; et al. Search on chromosome 17 centromere reveals TNFRSF13B as a susceptibility gene for intracranial aneurysm - A preliminary study. CIRCULATION 113:2002-2010(2006).
Nishio, J; Gentry, JD; et al. Monoallelic deletion of the p53 gene through chromosomal translocation in a small cell osteosarcoma. VIRCHOWS ARCHIV 448:852-856(2006).
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