Specifications
Immunogen
Synthetic peptide: C-QEQEDHDALKED, corresponding to internal sequence amino acids 448-459 of Human Nicotinic Acetylcholine Receptor beta (NP_000738.2).
Applications
Application Notes
Peptide ELISA: Antibody detection limit dilution 1/1000. WB: Use at a concentration of 1 - 3 μg/ml. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa). Not yet tested in other applications. Optimal dilutions/concentrations should
Target
Alternative Names
CHRNB1; cholinergic receptor, nicotinic, beta 1 (muscle); ACHRB; CHRNB; CMS1D; CMS2A; SCCMS; acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle);
Product Background
Antigen Description
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Pathway
Neuroactive ligand-receptor interaction;
Citations
Publication ()
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COA
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