Mouse anti-Human CHRNB1 polyclonal antibody

Species Reactivity

Human

Immunogen

CHRNB1 (NP_000738, 24 a.a. ~ 128 a.a) partial recombinant protein with GST tag. The sequence is SEAEGRLREKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEW TDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALD

Conjugate

Alternative Names

CHRNB1; cholinergic receptor, nicotinic, beta 1 (muscle); ACHRB; CHRNB; CMS1D; CMS2A; SCCMS; acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle);

Entrez Gene ID

UniProt ID

Antigen Description

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Pathway

Neuroactive ligand-receptor interaction;