Specifications
Immunogen
Synthetic peptide, corresponding to internal sequence amino acids 369-380 of Human Nicotinic Acetylcholine Receptor alpha 5 (NP_000736.2).
Applications
Application Notes
WB: 1 - 3 μg/ml; IHC-P: 3.75 μg/ml;
Target
Alternative Names
CHRNA5; cholinergic receptor, nicotinic, alpha 5 (neuronal); LNCR2; neuronal acetylcholine receptor subunit alpha-5; acetylcholine receptor, nicotinic, alpha 5 (neuronal); neuronal nicotinic acetylcholine receptor, alpha5 subunit; Cholinergic receptor, ne
Product Background
Antigen Description
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Pathway
Acetylcholine Binding And Downstream Events; Highly calcium permeable nicotinic acetylcholine receptors; Neuroactive ligand-receptor interaction; Neuronal System
Citations
Publication ()
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COA
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