Anti-CHRNA5 monoclonal antibody, clone FQS6406

Antibody Isotype

IgG

Clone

FQS6406

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide corresponding to residues in Human Nicotinic Acetylcholine Receptor alpha 5 (UniProt P30532).

Conjugate

Application Notes

WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; Flow Cyt: 1/10 - 1/100;

Alternative Names

CHRNA5; cholinergic receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 5; neuronal acetylcholine receptor subunit alpha-5; acetylcholine receptor; nicotinic; alpha 5 (neuronal); acetylcholine receptor, nicotinic, a

Entrez Gene ID

UniProt ID

Antigen Description

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Pathway

Acetylcholine Binding And Downstream Events, organism-specific biosystem; Activation of Nicotinic Acetylcholine Receptors, organism-specific biosystem; Highly calcium permeable nicotinic acetylcholine receptors, organism-specific biosystem; Highly calcium permeable postsynaptic nicotinic acetylcholine receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem; Neuronal System, organism-specific biosystem;