Rabbit Anti-Human CHMP4B (a.a. 1-224) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human CHMP4B protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-224 aa of BC033859

Conjugate

Application Notes

WB: 1:1000-1:8000
IF/ICC: 1:200-1:800

General Notes

This product (Catalog No. DPABH-25929) is a rabbit-derived polyclonal antibody raised against human CHMP4B, targeting the amino acid region 1–224 of the protein. This antibody exhibits cross-reactivity with Human CHMP4B from mouse and rat. It has been affinity purified by Protein A. CHMP4B (charged multivesicular body protein 4b) is a human homologue of yeast Snf7p (also named Vps32p) and a member of CHMP family which is implicated in multivesicular body (MVB) sorting. The CHMP proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies. Among seven CHMP family members, only CHMP4 has been found to interact with Alix, a multifunctional adaptor protein in various cellular functions.
DPABH-25929 is suitable for use in Western blot (WB) (1:1,000–1:8,000), IF/ICC (1:200–1:800) applications.
DPABH-25929 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

C20orf178; chromatin modifying protein 4B; Chromatin-modifying protein 4b; hSnf7-2; hVps32-2

Entrez Gene ID

UniProt ID