Specifications
Species Reactivity
Mouse; Human
Immunogen
Recombinant tagged fragment: CRDVISSEVG SDHELQAVLL TCLYLSYSYM GNEISYPLKP FLVESCKEAF WDRCLSVINL MSSKMLQINA DPHYFTQVFS DLKNESGQED KKRLLLGLDR, corresponding to amino acids 208-308 of Human p35
Applications
Application Notes
WB: 1 - 5 μg/ml; IHC-P: 5 μg/ml;
Target
Alternative Names
CDK5R1; cyclin-dependent kinase 5, regulatory subunit 1 (p35); cyclin-dependent kinase 5 activator 1; Nck5a; p35nck5a; CDK5 activator 1; neuronal CDK5 activator; TPKII regulatory subunit; regulatory partner for CDK5 kinase; tau protein kinase II 23kDa sub
Product Background
Antigen Description
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Activator of TPKII.
Pathway
Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Axon guidance, organism-specific biosystem; CRMPs in Sema3A signaling, organism-specific biosystem; Cocaine addiction, organism-specific biosystem; Cocaine addiction, conserved biosystem; Developmental Biology, organism-specific biosystem;
Citations
Publication ()
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COA
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