Rabbit Anti-Human CDH5 (C-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to residues near the C terminal of human cadherin 5, type 2 (vascular endothelium)

Conjugate

Application Notes

IHC: 1:50-1:200

General Notes

This product (Catalog No. DPABH-13812) is a rabbit-derived IgG polyclonal antibody raised against human CDH5. It has been affinity purified by protein A. This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
DPABH-13812 is suitable for use in IHC (1:50–1:200) application.
DPABH-13812 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

7B4; CD144

Entrez Gene ID

UniProt ID