Anti-CD80 monoclonal antibody (DMABT-H13342)
Mouse Anti-Human CD80 monoclonal antibody for IHC, IF, FC
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
NBC205
Species Reactivity
Human
Immunogen
Native purified CD80 from Jijoye cells (Human Burkitt Lymphoma cell line).
Conjugate
Unconjugated
Applications
Application Notes
Immunofluorescence (2ug/5x105cells/test ); Flow Cytometry (2ug/5x105cells/test ); Immunohistochemistry (Frozen sections)(1:20-1:50) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Target
Alternative Names
CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B72antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1
Entrez Gene ID
UniProt ID
Product Background
Pathway
Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem;
Citations
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References
Piconi, S; Trabattoni, D; et al. Immunological Effects of Sublingual Immunotherapy: Clinical Efficacy Is Associated with Modulation of Programmed Cell Death Ligand 1, IL-10, and IgG4. JOURNAL OF IMMUNOLOGY 185:7723-7730(2010).
Pathak, SK; Skold, AE; et al. Activated Apoptotic Cells Induce Dendritic Cell Maturation via Engagement of Toll-like Receptor 4 (TLR4), Dendritic Cell-specific Intercellular Adhesion Molecule 3 (ICAM-3)grabbing Nonintegrin (DC-SIGN), and beta 2 Integrins. JOURNAL OF BIOLOGICAL CHEMISTRY 287:13731-13742(2012).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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