Anti-CD80 monoclonal antibody (DMABT-H13342)

Mouse Anti-Human CD80 monoclonal antibody for IHC, IF, FC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
NBC205
Species Reactivity
Human
Immunogen
Native purified CD80 from Jijoye cells (Human Burkitt Lymphoma cell line).
Conjugate
Unconjugated

Applications


Application Notes
Immunofluorescence (2ug/5x105cells/test ); Flow Cytometry (2ug/5x105cells/test ); Immunohistochemistry (Frozen sections)(1:20-1:50) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B72antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem;

Citations


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References


Mahic, M; Henjum, K; et al. Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation. EUROPEAN JOURNAL OF IMMUNOLOGY 38:640-646(2008).
Tohyama, M; Watanabe, H; et al. Possible involvement of CD14+ CD16+ monocyte lineage cells in the epidermal damage of Stevens-Johnson syndrome and toxic epidermal necrolysis. BRITISH JOURNAL OF DERMATOLOGY 166:322-330(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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