Anti-CD3G (aa 23-111) polyclonal antibody

Species Reactivity

Human

Immunogen

CD3G (NP_000064, 23 a.a. ~ 111 a.a) partial recombinant protein with GST tag. The sequence is QSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGKMIGFLTEDKKKWNLGSNAKDPR GMYQCKGSQNKSKPLQVYYRMCQNCIELN

Conjugate

Alternative Names

CD3G; CD3g molecule, gamma (CD3-TCR complex); T3G; IMD17; CD3-GAMMA; T-cell surface glycoprotein CD3 gamma chain; T-cell receptor T3 gamma chain; CD3g molecule, epsilon (CD3-TCR complex); CD3g antigen, gamma polypeptide (TiT3 complex); T-cell antigen rece

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Pathway

Adaptive Immune System; Chagas disease (American trypanosomiasis); Costimulation by the CD28 family; Downstream signaling in naive CD8+ T cells