Anti-CD3G monoclonal antibody, clone 3B7

Antibody Isotype

IgG2a

Clone

3B7

Species Reactivity

Human

Immunogen

CD3G (NP_000064, 23 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

FLJ79544; FLJ94613; T3G; MGC138597; T-cell receptor T3 gamma chain; CD3-GAMMA; T-cell antigen receptor complex, gamma subunit of T3; FLJ17620; T-cell surface glycoprotein CD3 gamma chain; FLJ17664; OTTHUMP00000234565; CD3g molecule, epsilon (CD3-TCR compl

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
Mouse monoclonal antibody raised against a partial recombinant CD3G.

Pathway

Adaptive Immunity Signaling, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Downstream TCR signaling, organism-specific biosystem