Anti-CD274 monoclonal antibody, clone 2C23

Name: Anti-CD274 monoclonal antibody, clone 2C23
SKU: DCABH-6765
Rating: 5 (1 reviews)

Mouse anti-Human CD274 monoclonal antibody for WB

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG1

Clone

2C23

Species Reactivity

Human

Immunogen

Recombinant full length protein corresponding to Human CD274. Produced in HEK293T cells (NP_054862).Database link: Q9NZQ7

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/4000;

Target

Alternative Names

CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; B7-H; PD-L1; PDCD1L1; PDCD1LG1; M

Entrez Gene ID

29126

UniProt ID

Q0GN75

Product Background

Antigen Description

Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Pathway

Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem;

Citations