Anti-PDCD1LG1 Polyclonal Antibody (CABT-L2061) Knockout Validated

Rabbit Anti-Human PDCD1LG1 (Pro24~Pro234) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fragment corresponding to human CD274 (Pro24~Pro234)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml; 1:370-1500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type MB231 cell lysate. Lane 2: PDCD1LG1 knockout MB231 cell lysate. Predicted MW: 33, 20kDa, Observed MW: 33kDa
Figure. Western Blot. Sample. Lane1: Mouse Heart Tissue; Lane2: Rat Heart Tissue.
Western Blot. Sample. Porcine Heart lysate.
Western Blot. Sample. Porcine Skeletal muscle lysate.

Target


Alternative Names
CD274; PDL1; B7-H; B7H1; PD-L1; PDCD1L1
UniProt ID

Product Background


Pathway
Adaptive Immune System; Cell adhesion molecules (CAMs); Costimulation by the CD28 family; Immune System; PD-1 signaling;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Cole, P; et al. DURVALUMAB Human anti-PD-L1 monoclonal antibody Immune checkpoint inhibitor Oncolytic. DRUGS OF THE FUTURE 39:843-847(2014).
Jilaveanu, LB; Shuch, B; et al. PD-L1 Expression in Clear Cell Renal Cell Carcinoma: An Analysis of Nephrectomy and Sites of Metastases. JOURNAL OF CANCER 5:166-172(2014).

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