Anti-Human CD274 monoclonal antibody (CAB-722RH)

Rabbit Anti-Human CD274 monoclonal antibody for ELISA Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
2
Species Reactivity
Human
Immunogen
Recombinant Human B7-H1 protein
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution:
ELISA: 1:5000-1:10000
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CD274; CD274 molecule; B7-H; B7H1; PDL1; PD-L1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organismspecific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem;

Citations


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References


Aerts, JG; Hegmans, JP; et al. Tumor-Specific Cytotoxic T Cells Are Crucial for Efficacy of Immunomodulatory Antibodies in Patients with Lung Cancer. CANCER RESEARCH 73:2381-2388(2013).
Powles, T; Eder, JP; et al. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. NATURE 515:558-+(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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