Specifications
Immunogen
Recombinant Human B7-H1 protein
Applications
Application Notes
Recommended dilution:
ELISA: 1:5000-1:10000
Target
Alternative Names
CD274; CD274 molecule; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; programmed cell death 1 ligand 1; B7 homolog 1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; AMP-224
Product Background
Pathway
Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organismspecific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Gupta, N; Hegde, P; et al. Japanese encephalitis virus expands regulatory T cells by increasing the expression of PD-L1 on dendritic cells. EUROPEAN JOURNAL OF IMMUNOLOGY 44:1363-1374(2014).
Day, CL; Kaufmann, DE; et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. NATURE 443:350-354(2006).