Anti-PRNP monoclonal antibody (CABT-51048MS)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
5121
Species Reactivity
Sheep, Bovine, Cat, Chimpanzee, Dog, Goat, Gorilla, Human, Mouse, Pig, Rabbit, Rhesus monkey
Conjugate
Unconjugated

Applications


Application Notes
Immunohistology - Paraffin: 1/10 - 1/50; Western Blot: 1/10 - 1/50; ELISA: 1/20 - 1/200;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PRNP; Prp; SIP; PRPC; major prion protein; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
Entrez Gene ID
UniProt ID
P23907

Product Background


Pathway
Prion diseases;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Polymenidou, M; Stoeck, K; et al. Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease. LANCET NEUROLOGY 4:805-814(2005).
Giri, RK; Young, R; et al. Prion infection of mouse neurospheres. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 103:3875-3880(2006).

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