Anti-PRNP monoclonal antibody (DCABH-4696)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
6232
Species Reactivity
Sheep, Cow
Immunogen
Full length protein corresponding to Human Prion Protein PrP (UniProt: P04156).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/10 - 1/50; ELISA: 1/20 - 1/200; IHC-P: 1/10 - 1/50.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PRNP; prion protein; CJD, GSS, prion protein (p27 30) , PRIP; major prion protein; CD230; Creutzfeldt Jakob disease
Entrez Gene ID
UniProt ID

Product Background


Pathway
Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Glypican 1 network, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; NCAM1 interactions, organism-specific biosystem; Prion diseases, organism-specific biosystem; Prion diseases, conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Stanker, LH; Serban, AV; et al. Conformation-Dependent High-Affinity Monoclonal Antibodies to Prion Proteins. JOURNAL OF IMMUNOLOGY 185:729-737(2010).
Mitrova, E; Belay, G; et al. Creutzfeldt-Jakob disease with E200K mutation in Slovakia: Characterization and development. ACTA VIROLOGICA 46:31-39(2002).

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