Anti-CCND1 monoclonal antibody (DCABH-3360) Knockout Validated

Rabbit anti-Human CCND1 monoclonal antibody for WB, IHC-P, IP

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
TQ5
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide from the C-terminal region of Human Cyclin D1.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/100; IP: 1/20.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CCND1; cyclin D1; BCL1, cyclin D1 (PRAD1: parathyroid adenomatosis 1) , D11S287E, PRAD1; G1/S-specific cyclin-D1; B cell CLL/lymphoma 1; G1/S specific cyclin D1
Entrez Gene ID
UniProt ID

Product Background


Pathway
ATF-2 transcription factor network, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Balcerczak, E; Pasz-Walczak, G; et al. Cyclin D1 protein and CCND1 gene expression in colorectal cancer. EJSO 31:721-726(2005).
Gradowski, JF; Sargent, RL; et al. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma With Cyclin D1 Positive Proliferation Centers Do Not Have CCND1 Translocations or Gains and Lack SOX11 Expression. AMERICAN JOURNAL OF CLINICAL PATHOLOGY 138:132-139(2012).

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