CCNB1 (NP_114172, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. The sequence is MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM PMKKEAKPSATGKVIDKKLPKPLEKVPMLV
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
Pathway
AMPK signaling; APC/C:Cdc20 mediated degradation of Cyclin B; ATM Signaling Pathway; Activation of NIMA Kinases NEK9, NEK6, NEK7
Citations
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