Anti-CCNB1 monoclonal antibody, clone W263 Knockout Validated

Name: Anti-CCNB1 monoclonal antibody, clone W263
SKU: DCABH-9535
Rating: 5 (1 reviews)

Mouse anti-Human CCNB1 monoclonal antibody for SDS-PAGE, ICC/IF, IHC(PFA fixed), FC, WB, IHC-FoFr, IHC-P, IHC-Fr

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG1

Clone

W263

Species Reactivity

Human

Immunogen

His-tagged Hamster Cyclin B1 expressed in bacteria, harvested from inclusion bodies, extracted with 6M guanidine HCl and purified on Nickel beads.

Conjugate

Unconjugated

Applications

Application Notes

SDS-PAGE: 1/1500; IHC: 1/400; WB: 1 μg/ml; IHC-P: 5 μg/ml; IHC-Fr: 1 - 2 μg/ml.

Target

Alternative Names

CCNB1; cyclin B1; CCNB; G2/mitotic-specific cyclin-B1; G2/mitotic specific cyclin B1; G2/mitotic-specific cyclin B1;

Entrez Gene ID

891

UniProt ID

P14635

Product Background

Antigen Description

Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Pathway

APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem;

Citations