Anti-CCDC174 polyclonal antibody (DPABH-03055)

Rabbit anti-Human CCDC174 (aa 19-118) polyclonal antibody for IHC-P, ICC/IF

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to amino acids 19-118 of Human C3orf19.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1/20 - 1/50; ICC/IF: 1 - 4 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CCDC174; coiled-coil domain containing 174; C3orf19; coiled-coil domain-containing protein 174
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CCDC174 (Coiled-Coil Domain Containing 174) is a Protein Coding gene. Diseases associated with CCDC174 include infantile hypotonia and hypotonia. The protein encoded by this gene is found in the nucleus, where it interacts with eukaryotic translation initiation factor 4A, isoform 3. The encoded protein appears to be a part of the exon junction complex, which is involved in RNA processing, translation, and nonsense-mediated mRNA decay. A mutation in this gene has been associated with infantile hypotonia with psychomotor retardation.
Antigen Description
Protein Symbol:Q6PII3-CC174_HUMANRecommended name:Coiled-coil domain-containing protein 174Protein Accession:Q6PII3Secondary Accessions:Q96CS5.

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References


TANAKA, T; PARRY, DAD; et al. COMPARISON OF MOLECULARLY CLONED BULLOUS PEMPHIGOID ANTIGEN TO DESMOPLAKIN-I CONFIRMS THAT THEY DEFINE A NEW FAMILY OF CELL-ADHESION JUNCTION PLAQUE PROTEINS. JOURNAL OF BIOLOGICAL CHEMISTRY 266:12555-12559(1991).

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